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PMID: 99023 Published · ppublish English Journal Article Review

Hepatitis B vaccines. On the threshold.

American journal of clinical pathology ·Vol. 70 ·No. 1 Suppl ·1978-07-00 ·Pages 159-69

Purcell RH, Gerin JL

Abstract

Experimental hepatitis B vaccines have recently been developed and are undergoing preliminary evaluation. These vaccines are unique in that they are prepared from viral antigen purified from the plasmas of human chronic carriers because hepatitis B virus has not been cultivated in vitro. They appear to be safe and antigenic, but care must be exercised in their evaluation because of the potential risks inherent in all vaccines.

MeSH Terms
Animals Antigen-Antibody Reactions Antigens Blood Proteins Cost-Benefit Analysis Culture Techniques Drug Contamination Hepatitis B/epidemiology,immunology,microbiology,transmission Hepatitis B Antigens/classification Hepatitis B Core Antigens/isolation & purification Hepatitis B virus/immunology Herpesviridae/immunology Humans Liver Proteins Risk Viral Vaccines/adverse effects,isolation & purification
Chemicals
Antigens Blood Proteins Hepatitis B Antigens Hepatitis B Core Antigens Proteins Viral Vaccines
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Purcell R H
Gerin J L
Article Info
Journal
American journal of clinical pathology
Abbr.
Am J Clin Pathol
ISSN
0002-9173
Published
1978-07-00
Pages
159-69
Language
English
Region
England
NLM ID
0370470
Subset
IM
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