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PMID: 9847074 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Toward a complete human genome sequence.

Genome research ·Vol. 8 ·No. 11 ·1998-11-00 ·Pages 1097-108

Sanger Center, Genome Sequencing Center

Abstract

We have begun a joint program as part of a coordinated international effort to determine a complete human genome sequence. Our strategy is to map large-insert bacterial clones and to sequence each clone by a random shotgun approach followed by directed finishing. As of September 1998, we have identified the map positions of bacterial clones covering approximately 860 Mb for sequencing and completed >98 Mb ( approximately 3.3%) of the human genome sequence. Our progress and sequencing data can be accessed via the World Wide Web (http://webace.sanger.ac.uk/HGP/ or http://genome.wustl.edu/gsc/).

MeSH Terms
Contig Mapping DNA/chemistry,genetics Databases, Factual Genome, Human Genomic Library Human Genome Project Humans Internet Molecular Sequence Data Sequence Analysis, DNA/methods
Chemicals
DNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Sanger Center
Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK;
Genome Sequencing Center
Washington University School of Medicine, St. Louis, Missouri 63108 USA
Article Info
Journal
Genome research
Abbr.
Genome Res
ISSN
1088-9051
DOI
10.1101/gr.8.11.1097
Published
1998-11-00
Pages
1097-108
Language
English
Region
United States
NLM ID
9518021
Subset
IM
Databases
GENBANK
AC000066, AC002082, AC002483, AC003071, AC003073, AC003086, AC003982, AC004006, AC004007, AC004128, AC004263, AC004264, AC004453, AC004613, AC004744, AC004819, AC004829, AC004836, AC004841, AC004850, AC004856, AC004864, AC004876, AC004880, AC004883, AC004885, AC004886, AC004887, AC004890, AC004892
External Links
PubMed source DOI: 10.1101/gr.8.11.1097 View journal details
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