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PMID: 9839469 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Towards functional characterisation of the members of the R2R3-MYB gene family from Arabidopsis thaliana.

The Plant journal : for cell and molecular biology ·Vol. 16 ·No. 2 ·1998-10-00 ·Pages 263-76

Kranz HD, Denekamp M, Greco R, Jin H, Leyva A, Meissner RC, Petroni K, Urzainqui A, Bevan M, Martin C, Smeekens S, Tonelli C, Paz-Ares J, Weisshaar B

Abstract

Transcription factors containing a conserved DNA-binding domain similar to that of the proto-oncogene c-myb have been identified in nearly all eukaryotes. MYB-related proteins from plants generally contain two related helix-turn-helix motifs, the R2 and R3 repeats. It was estimated that Arabidopsis thaliana contains more than 100 R2R3-MYB genes. The few cases where functional data are available suggest an important role of these genes in the regulation of secondary metabolism, the control of cell shape, disease resistance, and hormone responses. To determine the full regulatory potential of this large family of regulatory genes, a systematic search for the function of all genes of this family was initiated. Sequence data for more than 90 different A. thaliana R2R3-MYB genes have been obtained. Sequence comparison revealed conserved amino acid motifs shared by subgroups of R2R3-MYB genes in addition to the characteristic DNA-binding domain. No significant clustering of the genes was detected, although they are not uniformly distributed throughout the A. thaliana genome.

MeSH Terms

Amino Acid Sequence Arabidopsis/genetics Arabidopsis Proteins/genetics Chromosome Mapping Chromosomes DNA-Binding Proteins/genetics Genome, Plant Helix-Turn-Helix Motifs/genetics Molecular Sequence Data Plant Proteins/genetics Polymerase Chain Reaction Proto-Oncogene Proteins c-myb Transcription Factors/genetics

Chemicals

ATR1 protein, Arabidopsis Arabidopsis Proteins CPC protein, Arabidopsis DNA-Binding Proteins MYB21 protein, Arabidopsis MYB24 protein, Arabidopsis Plant Proteins Proto-Oncogene Proteins c-myb RAX2 protein, Arabidopsis Transcription Factors

Authors & Affiliations

14 authors, click to expand affiliations / ORCID

Kranz H D

Max-Planck Institut für Züchtungsforschung, Abteilung Biochemie, Köln, Germany.

Denekamp M

Greco R

Jin H

Leyva A

Meissner R C

Petroni K

Urzainqui A

Bevan M

Martin C

Smeekens S

Tonelli C

Paz-Ares J

Weisshaar B

Article Info

Journal

The Plant journal : for cell and molecular biology

Abbr.

Plant J

ISSN

0960-7412

DOI

10.1046/j.1365-313x.1998.00278.x

Published

1998-10-00

Pages

263-76

Language

English

Region

England

NLM ID

9207397

Subset

Databases

GENBANK

AF062859, AF062860, AF062861, AF062862, AF062863, AF062864, AF062865, AF062866, AF062867, AF062868, AF062869, AF062870, AF062871, AF062872, AF062873, AF062874, AF062875, AF062876, AF062877, AF062878, AF062879, AF062880, AF062881, AF062882, AF062883, AF062884, AF062885, AF062886, AF062887, AF062888

External Links

PubMed source DOI: 10.1046/j.1365-313x.1998.00278.x View journal details

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Towards functional characterisation of the members of the R2R3-MYB gene family from Arabidopsis thaliana.

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