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PMID: 9811620 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

RNA trafficking in myelinating cells.

Current opinion in neurobiology ·Vol. 8 ·No. 5 ·1998-10-00 ·Pages 607-12

Carson JH, Kwon S, Barbarese E

Abstract

In the past year, several key molecular components of the RNA trafficking pathway in myelinating cells have been identified: distinct cis-acting elements for RNA transport and localization have been characterized in myelin basic protein mRNA; hnRNP A2 has been identified as a trans-acting factor in oligodendrocytes that binds specifically to the RNA transport sequence; and microtubules and kinesin have been identified as cytoskeletal elements required for RNA transport in oligodendrocytes.

MeSH Terms
Animals Biological Transport/physiology Myelin Sheath/metabolism Oligodendroglia/metabolism RNA, Messenger/metabolism
Chemicals
RNA, Messenger
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Carson J H
Department of Biochemistry, University of Connecticut Health Center, Farmington 06030, USA. jcarson@nso2.uchc.edu
Kwon S
Barbarese E
Article Info
Journal
Current opinion in neurobiology
Abbr.
Curr Opin Neurobiol
ISSN
0959-4388
Published
1998-10-00
Pages
607-12
Language
English
Region
England
NLM ID
9111376
Subset
IM
Grants
NINDS NIH HHS · NS15190 · United States
NINDS NIH HHS · NS19943 · United States
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