Replication conrol: choreographing replication origins.

Current biology : CB ·Vol. 8 ·No. 21 ·1998-10-22 ·Pages R771-3

Diffley JF

Abstract

Budding yeast replication origins are activated during S phase according to a predetermined temporal programme. Two recent studies indicate that this programme is executed, at least in part, by the S-phase-promoting cyclins that act to assemble a pre-initiation complex which includes the Cdc45 protein.

MeSH Terms

Carrier Proteins/metabolism Cyclins/physiology DNA Replication DNA-Binding Proteins Fungal Proteins/metabolism Models, Genetic Nuclear Proteins/metabolism Replication Origin S Phase Saccharomyces cerevisiae/cytology,genetics,physiology Saccharomyces cerevisiae Proteins

Chemicals

CDC45 protein, S cerevisiae Carrier Proteins Cyclins DNA-Binding Proteins Fungal Proteins Nuclear Proteins Saccharomyces cerevisiae Proteins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Diffley J F

ICRF Clare Hall Laboratories South Mimms, Hertfordshire, EN6 3LD, UK. J.Diffley@icrf.icnet.uk

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(07)00483-6

j.diffley@icrf.icnet.uk

Published

1998-10-22

Pages

R771-3

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(07)00483-6 View journal details

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