Home LiteratureArticle Details
PMID: 9788947 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Symmetry laws for interaction between helical macromolecules.

Biophysical journal ·Vol. 75 ·No. 5 ·1998-11-00 ·Pages 2513-9

Kornyshev AA, Leikin S

Abstract

The power of symmetry laws is applied in many scientific areas from elementary particle physics to structural biology. The structures of many biological helices, including DNA, were resolved with the use of pertinent symmetry constraints. It was not recognized, however, that similar constraints determine cardinal features of helix-helix interactions vital for many recognition and assembly reactions in living cells. We now formulate such symmetry-determined interaction laws and apply them to explain DNA "over-winding" from 10.5 base pairs per turn in solution to 10 in hydrated fibers, counterion specificity in DNA condensation, and forces observed over the last 15 A of separation between DNA, collagen, and four-stranded guanosine helices.

MeSH Terms
DNA/chemistry Macromolecular Substances Models, Molecular Static Electricity
Chemicals
Macromolecular Substances DNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kornyshev A A
Research Center "Jülich," D-52425 Jülich, Germany.
Leikin S
References (28)
28 references, click to expand
  1. Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution.
    Science. 1994 Oct 7;266(5182):75-81 PMID: 7695699
  2. Molecular structure of nucleic acids; a structure for deoxyribose nucleic acid.
    Nature. 1953 Apr 25;171(4356):737-8 PMID: 13054692
  3. Monomolecular condensation of lambda-DNA induced by cobalt hexamine.
    Biopolymers. 1983 Jun;22(6):1595-620 PMID: 6223670
  4. Measurement of the repulsive force between polyelectrolyte molecules in ionic solution: hydration forces between parallel DNA double helices.
    Proc Natl Acad Sci U S A. 1984 May;81(9):2621-5 PMID: 6585818
  5. Hydration structure of a collagen peptide.
    Structure. 1995 Sep 15;3(9):893-906 PMID: 8535783
  6. Solvent hydrogen-bond network in protein self-assembly: solvation of collagen triple helices in nonaqueous solvents.
    Biophys J. 1997 Jan;72(1):353-62 PMID: 8994620
  7. Helical parameters of DNA do not change when DNA fibers are wetted: X-ray diffraction study.
    Proc Natl Acad Sci U S A. 1979 Jun;76(6):2703-7 PMID: 288058
  8. Role of hydration and water structure in biological and colloidal interactions.
    Nature. 1996 Jan 18;379(6562):219-25 PMID: 8538786
  9. Direct measurement of forces between self-assembled proteins: temperature-dependent exponential forces between collagen triple helices.
    Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):276-80 PMID: 8278378
  10. Helical periodicity of DNA determined by enzyme digestion.
    Nature. 1980 Aug 7;286(5773):573-8 PMID: 7402337
  11. Molecular structure of deoxypentose nucleic acids.
    Nature. 1953 Apr 25;171(4356):738-40 PMID: 13054693
  12. Direct measurement of the intermolecular forces between counterion-condensed DNA double helices. Evidence for long range attractive hydration forces.
    Biophys J. 1992 Jan;61(1):246-59 PMID: 1540693
  13. Temperature-favoured assembly of collagen is driven by hydrophilic not hydrophobic interactions.
    Nat Struct Biol. 1995 Mar;2(3):205-10 PMID: 7773789
  14. Direct measurement of forces between linear polysaccharides xanthan and schizophyllan.
    Science. 1990 Sep 14;249(4974):1278-81 PMID: 2144663
  15. DNA bending, flexibility, and helical repeat by cyclization kinetics.
    Methods Enzymol. 1992;212:3-29 PMID: 1518450
  16. Molecular structure of the B-DNA dodecamer d(CGCAAATTTGCG)2. An examination of propeller twist and minor-groove water structure at 2.2 A resolution.
    J Mol Biol. 1992 Aug 20;226(4):1161-73 PMID: 1518049
  17. DNA condensation.
    Curr Opin Struct Biol. 1996 Jun;6(3):334-41 PMID: 8804837
  18. DNA condensation with polyamines I. Spectroscopic studies.
    J Mol Biol. 1978 May 25;121(3):311-26 PMID: 671540
  19. Hydration forces.
    Annu Rev Phys Chem. 1993;44:369-95 PMID: 8257560
  20. Raman spectral evidence for hydration forces between collagen triple helices.
    Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11312-7 PMID: 9326606
  21. Direct measurement of temperature-dependent solvation forces between DNA double helices.
    Biophys J. 1992 Jan;61(1):260-71 PMID: 1540694
  22. Analytical Debye-Huckel model for electrostatic potentials around dissolved DNA.
    Biophys J. 1997 Jul;73(1):21-30 PMID: 9199767
  23. Helix-specific interactions induce condensation of guanosine four-stranded helices in concentrated salt solutions.
    Biophys J. 1998 Jan;74(1):430-5 PMID: 9449343
  24. Measurement of intercolumnar forces between parallel guanosine four-stranded helices.
    Biophys J. 1996 Jun;70(6):2867-74 PMID: 8744324
  25. Hydration and steric pressures between phospholipid bilayers.
    Annu Rev Biophys Biomol Struct. 1994;23:27-51 PMID: 7919783
  26. Fluctuation theory of hydration forces: The dramatic effects of inhomogeneous boundary conditions.
    Phys Rev A Gen Phys. 1989 Dec 1;40(11):6431-6437 PMID: 9902040
  27. The electrostatic potential of B-DNA.
    Biopolymers. 1989 May;28(5):975-93 PMID: 2742988
  28. DNA aggregation induced by polyamines and cobalthexamine.
    J Biol Chem. 1996 Mar 8;271(10):5656-62 PMID: 8621429
Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
DOI
10.1016/S0006-3495(98)77696-9
Published
1998-11-00
Pages
2513-9
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1299926
Subset
IM
External Links
PubMed source DOI: 10.1016/S0006-3495(98)77696-9 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2