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题目:: A comparative study on the efficacy of CD8-positive cells in enhancing allogeneic bone marrow engraftment: cell sorting vs microbead selection.
作者:: Sen-Majumdar(A),Sheehan(K),Guo(G),Allegre(G),Simone(J),Harvey(M),Chow(P),Moen(R),Smith(A)
状态:: 发布时间1998-11-17 , 更新时间 2006-11-15
期刊:: Bone Marrow Transplant
摘要:: We have used a superparamagnetic microbead selection system to positively select a murine bone marrow CD8+ cell population. The functional ability of these cells to enhance allogeneic bone marrow engraftment was compared with that of fluorescence activated cell sorter purified CD8+ cells. The CD8+ cell population prepared by the microbead selection procedure was as effective as cell sorter purified CD8+ cells in enhancing T cell-depleted allogeneic bone marrow engraftment in lethally irradiated mice. Phenotypic characterization of these cells shows that most of these CD8+ cells express CD3 and the T cell antigen receptor complex.
语言:: eng
DOI:: 10.1038/sj.bmt.1701350

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