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题目:: T cells expressing killer cell inhibitory receptors do not carry TCR for alloantigens.
作者:: Yamada(N),Nagatani(T),Takiguchi(M)
状态:: 发布时间1998-10-05 , 更新时间 2007-11-15
期刊:: Hum Immunol
摘要:: The role of T cells carrying the killer cell inhibitory receptor (KIR) is unknown. Here we investigate the allo-response of KIR+ CD3+ cells (KIR+ T cells). KIR+ T cells was found in 4.6-14.7% of the T cells from the PBMC of healthy individuals. Flow cytometry analysis showed that the percentage of KIR+ T cells in T cells from three individuals was decreased after stimulation with allogeneic PBMC. These findings suggest that KIR+ T cells do not respond to alloantigens. Furthermore, the analyses using purified KIR+ T cells also confirmed that KIR+ T cells do not respond to alloantigens.
语言:: eng
DOI:

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