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PMID: 9699460 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Gene clusters and polycistronic transcription in eukaryotes.

BioEssays : news and reviews in molecular, cellular and developmental biology ·Vol. 20 ·No. 6 ·1998-06-00 ·Pages 480-7

Blumenthal T

Abstract

Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre-mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants.

MeSH Terms

Alternative Splicing Animals Base Sequence Caenorhabditis elegans/genetics Drosophila/genetics Eukaryotic Cells Evolution, Molecular Genes Multigene Family Operon Plants/genetics RNA, Messenger/genetics Transcription, Genetic Trypanosoma/genetics

Chemicals

RNA, Messenger

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Blumenthal T

Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center, Denver 80262, USA. Tom.Blumenthal@uchsc.edu

Article Info

Journal

BioEssays : news and reviews in molecular, cellular and developmental biology

Abbr.

Bioessays

ISSN

0265-9247

DOI

10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q

tom.blumenthal@uchsc.edu

Published

1998-06-00

Pages

480-7

Language

English

Region

United States

NLM ID

8510851

Subset

Grants

NIGMS NIH HHS · GM42432 · United States

External Links

PubMed source DOI: 10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q View journal details

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