GABAB receptors: drugs meet clones.

Current opinion in neurobiology ·Vol. 8 ·No. 3 ·1998-06-00 ·Pages 345-50

Bettler B, Kaupmann K, Bowery N

Abstract

Recently, the long-awaited cloning of the GABAB receptors, the last of the major known neurotransmitter receptors to be identified, has been reported. In addition to an emerging molecular understanding, there have been advances in discerning the specific coupling partners of GABAB receptors in the brain.

MeSH Terms

Baclofen/therapeutic use Brain Chemistry/physiology Cloning, Molecular GABA Agonists/therapeutic use GABA-B Receptor Agonists Humans Receptors, GABA-B/chemistry,genetics Signal Transduction/physiology gamma-Aminobutyric Acid/physiology

Chemicals

GABA Agonists GABA-B Receptor Agonists Receptors, GABA-B gamma-Aminobutyric Acid Baclofen

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Bettler B

Novartis Pharma, Basel, Switzerland. bernhard.bettler@pharma.novartis.com

Kaupmann K

Bowery N

Article Info

Journal

Current opinion in neurobiology

Abbr.

Curr Opin Neurobiol

ISSN

0959-4388

DOI

10.1016/s0959-4388(98)80059-7

bernhard.bettler@pharma.novartis.com

Published

1998-06-00

Pages

345-50

Language

English

Region

England

NLM ID

9111376

Subset

External Links

PubMed source DOI: 10.1016/s0959-4388(98)80059-7 View journal details

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GABAB receptors: drugs meet clones.

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