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PMID: 962858 Published · ppublish English Journal Article

Presence of type III collagen in guinea-pig dermal scar.

The Biochemical journal ·Vol. 157 ·No. 1 ·1976-07-01 ·Pages 263-6

Barnes MJ, Morton LF, Bennett RC, Bailey AJ, Sims TJ

Abstract

Guinea-pig dermal scar was shown to contain type III collagen, and, from densitometric analysis of gel electrophoretograms, it was shown to have a higher concentration than the surrounding dermis. This finding is consistent with the 'embryonic' nature of newly formed dermal wound tissue, reflected in increased hydroxylation of collagen lysine and the presence of dihydroxylysinonorleucine (after reduction) as the major cross-link.

MeSH Terms
Animals Cicatrix Collagen/analysis Guinea Pigs Hydroxylation Lysine/analysis Skin/analysis
Chemicals
Collagen Lysine
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Barnes M J
Morton L F
Bennett R C
Bailey A J
Sims T J
References (20)
20 references, click to expand
  1. Identification of three genetically distinct collagens by cyanogen bromide cleavage of insoluble human skin and cartilage collagen.
    Biochem Biophys Res Commun. 1971 Mar 19;42(6):1024-9 PMID: 5550793
  2. Age-related variations in hydroxylation of lysine and proline in collagen.
    Biochem J. 1974 May;139(2):461-8 PMID: 4447620
  3. (Alpha1(3))3 human skin collagen. Release by pepsin digestion and preponderance in fetal life.
    J Biol Chem. 1974 May 25;249(10):3225-31 PMID: 4598122
  4. Collagen polymorphism: characterization of molecules with the chain composition (alpha 1 (3)03 in human tissues.
    Science. 1974 Mar;183(130):1200-1 PMID: 4812351
  5. Molecular weight heterogeneity of the alpha-chain sub-units of collagen.
    Biochem Biophys Res Commun. 1971 Apr 16;43(2):340-5 PMID: 5577447
  6. Hydroxylysine in the N-terminal regions of the 1 - and 2 -chains of various collagens.
    Biochem J. 1971 Nov;125(2):433-7 PMID: 5144746
  7. Chemistry of the collagen cross-links. Nature of the cross-links in the polymorphic forms of dermal collagen during development.
    Biochem J. 1976 Feb 1;153(2):211-5 PMID: 179531
  8. Embryonic skin collagen. Replacement of the type of aldimine crosslinks during the early growth period.
    FEBS Lett. 1972 Apr 1;21(3):330-334 PMID: 11946539
  9. Comparison of the cyanogen bromide peptides of insoluble guinea-pig skin and scar collagen.
    Biochim Biophys Acta. 1975 Jan 30;379(1):207-16 PMID: 1115796
  10. Pepsin-solubilized collagens of guinea-pig dermis and dermal scar.
    Biochim Biophys Acta. 1974 Oct 9;365(2):454-7 PMID: 4609476
  11. Studies in vivo on the biosynthesis of collagen and elastin in ascorbic acid-deficient guinea pigs. Evidence for the formation and degradation of a partially hydroxylated collagen.
    Biochem J. 1970 Sep;119(3):575-85 PMID: 5500318
  12. Evidence for procollagen, a biosynthetic precursors of collagen.
    Proc Natl Acad Sci U S A. 1971 Jun;68(6):1138-42 PMID: 4942180
  13. Characterization of the collagen of human hypertrophic and normal scars.
    Biochim Biophys Acta. 1975 Oct 20;405(2):412-21 PMID: 1180964
  14. Changes in the nature of the collagen during development and resorption of granulatin tissue.
    Biochim Biophys Acta. 1973 Dec 6;328(2):383-90 PMID: 4776451
  15. Recommendations concerning the use of bacterial collagenase for isolating collagen-associated molecules from tissues.
    Anal Biochem. 1973 May;53(1):313-6 PMID: 4351122
  16. Changes in guinea-pig dermal collagen during development.
    Eur J Biochem. 1975 Jul 1;55(2):391-5 PMID: 1201754
  17. The chemistry of the collagen cross-links. Age-related changes in the reducible components of intact bovine collagen fibres.
    Biochem J. 1973 Apr;131(4):771-80 PMID: 4722452
  18. Hydroxylysine in the N-terminal telopeptides of skin collagen from chick embryo and newborn rat.
    Biochem J. 1971 Dec;125(3):925-8 PMID: 5145913
  19. A comparison between the reducible intermolecular crosslinks of the collagens from mature dermis and young dermal scar tissue of the guinea pig.
    Biochem Biophys Res Commun. 1972 Mar 10;46(5):1776-81 PMID: 5015228
  20. Collagen polymorphism in experimental granulation tissue.
    Biochem Biophys Res Commun. 1975 Oct 27;66(4):1160-5 PMID: 1191284
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1976-07-01
Pages
263-6
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1163841
Subset
IM
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