Home LiteratureArticle Details

PMID: 9586772 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

No difference in hippocampus volume detected on magnetic resonance imaging in autistic individuals.

Journal of autism and developmental disorders ·Vol. 28 ·No. 2 ·1998-04-00 ·Pages 105-10

Piven J, Bailey J, Ranson BJ, Arndt S

Abstract

Neuropathological and animal studies have implicated the hippocampus as having a potential role in autism. Current imaging methods are well suited to the detailed measurement of the volume of the hippocampus, which has received little attention in previous imaging studies in autism. We report the results of a magnetic resonance imaging (MRI) study of 35 autistic and 36 control subjects. Detailed (1.5 mm) MRI did not reveal differences in the volume of the hippocampus in autistic individuals.

MeSH Terms

Adolescent Adult Autistic Disorder/diagnosis Female Hippocampus/abnormalities Humans Magnetic Resonance Imaging Male Neuropsychological Tests

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Piven J

The Department of Psychiatry, University of Iowa, Iowa City, USA.

Bailey J

Ranson B J

Arndt S

References (14)

14 references, click to expand

Regional brain enlargement in autism: a magnetic resonance imaging study.
J Am Acad Child Adolesc Psychiatry. 1996 Apr;35(4):530-6 PMID: 8919716
Image processing for the study of brain structure and function: problems and programs.
J Neuropsychiatry Clin Neurosci. 1992 Spring;4(2):125-33 PMID: 1627972
Evaluating and validating two methods for estimating brain structure volumes: tessellation and simple pixel counting.
Neuroimage. 1994 Jun;1(3):191-8 PMID: 9343570
Segmentation techniques for the classification of brain tissue using magnetic resonance imaging.
Psychiatry Res. 1992 May;45(1):33-51 PMID: 1410077
Autism, amnesia, hippocampus, and learning.
Neurosci Biobehav Rev. 1992 Spring;16(1):63-70 PMID: 1553107
Variability of corpus callosal area measurements from midsagittal MR images: effect of subject placement within the scanner.
AJNR Am J Neuroradiol. 1996 Jan;17(1):27-8 PMID: 8770245
Cross-sectional area of the posterior hippocampus in autistic patients with cerebellar and corpus callosum abnormalities.
Neurology. 1995 Feb;45(2):317-24 PMID: 7854533
Landmark-based registration and measurement of magnetic resonance images: a reliability study.
Psychiatry Res. 1996 Jul 31;67(2):145-54 PMID: 8876014
Magnetic resonance imaging in autism: measurement of the cerebellum, pons, and fourth ventricle.
Biol Psychiatry. 1992 Mar 1;31(5):491-504 PMID: 1581425
Autism diagnostic interview: a standardized investigator-based instrument.
J Autism Dev Disord. 1989 Sep;19(3):363-87 PMID: 2793783
Automatic atlas-based volume estimation of human brain regions from MR images.
J Comput Assist Tomogr. 1996 Jan-Feb;20(1):98-106 PMID: 8576490
Anatomic basis of amygdaloid and hippocampal volume measurement by magnetic resonance imaging.
Neurology. 1992 Sep;42(9):1743-50 PMID: 1513464
Techniques for measuring sulcal/gyral patterns in the brain as visualized through magnetic resonance scanning: BRAINPLOT and BRAINMAP.
Proc Natl Acad Sci U S A. 1994 Jan 4;91(1):93-7 PMID: 8278413
Diagnosis, treatment, and neurobiology of autism in children.
Curr Opin Pediatr. 1995 Aug;7(4):392-400 PMID: 7581642

Article Info

Journal

Journal of autism and developmental disorders

Abbr.

J Autism Dev Disord

ISSN

0162-3257

DOI

10.1023/a:1026084430649

Published

1998-04-00

Pages

105-10

Language

English

Region

United States

NLM ID

7904301

Subset

Grants

NIMH NIH HHS · MH01028 · United States

NIMH NIH HHS · MH40856 · United States

NIMH NIH HHS · MH51217 · United States

Corrections

ErratumIn

External Links

PubMed source DOI: 10.1023/a:1026084430649 View journal details

Analysis Services

No difference in hippocampus volume detected on magnetic resonance imaging in autistic individuals.

Contact

WeChat Official Account