Home LiteratureArticle Details
PMID: 9565628 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The multiplex function of nitric oxide in (auto)immunity.

The Journal of experimental medicine ·Vol. 187 ·No. 9 ·1998-05-04 ·Pages 1361-5

Bogdan C

Abstract

暂无摘要

MeSH Terms
Animals Autoimmunity/immunology Cytokines/pharmacology Encephalitis/immunology,physiopathology Humans Mice Nephritis/immunology Nitric Oxide/physiology Nitric Oxide Synthase/physiology Rats Uveitis/immunology
Chemicals
Cytokines Nitric Oxide Nitric Oxide Synthase
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Bogdan C
Institute of Clinical Microbiology, Immunology and Hygiene, University of Erlangen, D-91054 Erlangen, Germany. christian.bogdan@mikrobio.med.uni-erlangen.de
References (40)
40 references, click to expand
  1. Suppression of arthritis by an inhibitor of nitric oxide synthase.
    J Exp Med. 1993 Aug 1;178(2):749-54 PMID: 7688035
  2. Septic arthritis following Staphylococcus aureus infection in mice lacking inducible nitric oxide synthase.
    J Immunol. 1998 Jan 1;160(1):308-15 PMID: 9551985
  3. Aminoguanidine, an inhibitor of inducible nitric oxide synthase, ameliorates experimental autoimmune encephalomyelitis in SJL mice.
    J Clin Invest. 1994 Jun;93(6):2684-90 PMID: 7515395
  4. Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis.
    J Neuroimmunol. 1995 Apr;58(1):81-8 PMID: 7537283
  5. Roles of nitric oxide in tumor growth.
    Proc Natl Acad Sci U S A. 1995 May 9;92(10):4392-6 PMID: 7538668
  6. Regulation of lymphocyte functions by nitric oxide.
    Curr Opin Immunol. 1995 Jun;7(3):396-9 PMID: 7546406
  7. Inducible nitric oxide synthase and its product nitric oxide, a small molecule with complex biological activities.
    Biol Chem Hoppe Seyler. 1995 Jun;376(6):327-43 PMID: 7576227
  8. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).
    J Immunol. 1996 Jan 1;156(1):5-7 PMID: 8598493
  9. Experimental allergic encephalomyelitis in the rat is inhibited by aminoguanidine, an inhibitor of nitric oxide synthase.
    J Neuroimmunol. 1996 Feb;64(2):123-33 PMID: 8632054
  10. Aggravation of experimental allergic encephalomyelitis (EAE) by administration of nitric oxide (NO) synthase inhibitors.
    Clin Exp Immunol. 1996 Mar;103(3):467-74 PMID: 8608648
  11. Activation of nitric oxide synthase gene for inhibition of cancer metastasis.
    J Leukoc Biol. 1996 Jun;59(6):797-803 PMID: 8691063
  12. L-N6-(1-iminoethyl)-lysine potently inhibits inducible nitric oxide synthase and is superior to NG-monomethyl-arginine in vitro and in vivo.
    Eur J Pharmacol. 1995 Dec 29;294(2-3):703-12 PMID: 8750736
  13. Association of CD4+ T cell-dependent, interferon-gamma-mediated necrosis of the small intestine with genetic susceptibility of mice to peroral infection with Toxoplasma gondii.
    J Exp Med. 1996 Aug 1;184(2):597-607 PMID: 8760813
  14. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis.
    J Immunol. 1996 Oct 15;157(8):3223-7 PMID: 8871615
  15. Aminoguanidine and its pro-oxidant effects on an experimental model of protein glycation.
    Free Radic Biol Med. 1996;21(6):801-12 PMID: 8902526
  16. An essential role for free radicals and derived species in signal transduction.
    FASEB J. 1997 Feb;11(2):118-24 PMID: 9039953
  17. Nitric oxide via an inducible isoform of nitric oxide synthase is a possible factor to eliminate inflammatory cells from the central nervous system of mice with experimental allergic encephalomyelitis.
    J Neuroimmunol. 1997 Mar;73(1-2):107-16 PMID: 9058766
  18. Inhibition of nitric oxide synthase for treatment of experimental autoimmune encephalomyelitis.
    J Immunol. 1997 Mar 15;158(6):2940-6 PMID: 9058833
  19. Prevention of experimental allergic encephalomyelitis by targeting nitric oxide and peroxynitrite: implications for the treatment of multiple sclerosis.
    Proc Natl Acad Sci U S A. 1997 Mar 18;94(6):2528-33 PMID: 9122229
  20. Astrocytes and microglia express inducible nitric oxide synthase in mice with experimental allergic encephalomyelitis.
    J Neuroimmunol. 1997 Apr;74(1-2):121-9 PMID: 9119964
  21. Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondii.
    J Exp Med. 1997 Apr 7;185(7):1261-73 PMID: 9104813
  22. Nitric oxide and macrophage function.
    Annu Rev Immunol. 1997;15:323-50 PMID: 9143691
  23. Apoptosis of myelin-reactive T cells induced by reactive oxygen and nitrogen intermediates in vitro.
    Cell Immunol. 1997 May 25;178(1):1-8 PMID: 9184692
  24. Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.
    J Clin Invest. 1997 Jun 15;99(12):2818-25 PMID: 9185502
  25. IFN-gamma-deficient mice develop experimental autoimmune uveitis in the context of a deviant effector response.
    J Immunol. 1997 Jun 15;158(12):5997-6005 PMID: 9190954
  26. Expression of inducible nitric oxide synthase in breast cancer correlates with metastatic disease.
    Mod Pathol. 1997 Jul;10(7):645-9 PMID: 9237172
  27. Of microbes, macrophages and nitric oxide.
    Behring Inst Mitt. 1997 Mar;(99):58-72 PMID: 9303203
  28. Nitric oxide accelerates the onset and increases the severity of experimental autoimmune uveoretinitis through an IFN-gamma-dependent mechanism.
    J Immunol. 1997 Nov 15;159(10):5132-42 PMID: 9366443
  29. A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice.
    Proc Natl Acad Sci U S A. 1997 Dec 9;94(25):13955-60 PMID: 9391134
  30. Nitric oxide and the immunomodulation of experimental allergic encephalomyelitis.
    Eur J Immunol. 1997 Nov;27(11):2863-9 PMID: 9394811
  31. Nitric oxide synthases: which, where, how, and why?
    J Clin Invest. 1997 Nov 1;100(9):2146-52 PMID: 9410890
  32. Inducible nitric oxide synthase: what difference does it make?
    J Clin Invest. 1997 Nov 15;100(10):2417-23 PMID: 9366554
  33. Nitric oxide and thiol redox regulation of Janus kinase activity.
    Proc Natl Acad Sci U S A. 1998 Jan 6;95(1):126-31 PMID: 9419340
  34. Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite.
    Immunity. 1998 Jan;8(1):77-87 PMID: 9462513
  35. An interleukin (IL)-10/IL-12 immunoregulatory circuit controls susceptibility to autoimmune disease.
    J Exp Med. 1998 Feb 16;187(4):537-46 PMID: 9463404
  36. Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock.
    J Exp Med. 1998 Mar 16;187(6):917-28 PMID: 9500794
  37. Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice.
    J Immunol. 1998 Mar 15;160(6):2560-4 PMID: 9510151
  38. Experimental autoimmune encephalomyelitis is exacerbated in mice lacking the NOS2 gene.
    J Immunol. 1998 Mar 15;160(6):2940-6 PMID: 9510198
  39. Inhibition of inducible nitric oxide synthase intensifies injury and functional deterioration in autoimmune interstitial nephritis.
    J Immunol. 1997 Dec 15;159(12):6266-75 PMID: 9550431
  40. The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.
    J Exp Med. 1994 Feb 1;179(2):651-60 PMID: 7507509
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.187.9.1361
Email
christian.bogdan@mikrobio.med.uni-erlangen.de
Published
1998-05-04
Pages
1361-5
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2212276
Subset
IM
External Links
PubMed source DOI: 10.1084/jem.187.9.1361 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2