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PMID: 9507641 Published · ppublish English Journal Article Review

Instruments of microbial warfare: bacteriocin synthesis, toxicity and immunity.

Trends in microbiology ·Vol. 6 ·No. 2 ·1998-02-00 ·Pages 66-71

Baba T, Schneewind O

Abstract

Bacteria have devised ingenious enzymatic machinery to synthesize antibiotic molecules (bacteriocins) for their continuous warfare with other microorganisms. Synthesis and export of these toxic compounds are coordinated to ensure the proper extracellular activation of bacteriocin toxicity. In designing future antibiotics, some of the tricks used by bacteriocins might be exploited for the synthesis of novel compounds.

MeSH Terms
Amino Acid Sequence Anti-Bacterial Agents Bacteriocins/biosynthesis,pharmacology Models, Biological Molecular Sequence Data Protein Processing, Post-Translational Species Specificity
Chemicals
Anti-Bacterial Agents Bacteriocins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Baba T
Dept of Microbiology & Immunology, UCLA School of Medicine 90095, USA. tbaba@ucla.edu
Schneewind O
Article Info
Journal
Trends in microbiology
Abbr.
Trends Microbiol
ISSN
0966-842X
Published
1998-02-00
Pages
66-71
Language
English
Region
England
NLM ID
9310916
Subset
IM
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