Home LiteratureArticle Details
PMID: 9433137 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

STAR, a gene family involved in signal transduction and activation of RNA.

Trends in genetics : TIG ·Vol. 13 ·No. 12 ·1997-12-00 ·Pages 479-84

Vernet C, Artzt K

Abstract

A new subfamily of KH-domain-containing RNA-binding proteins is encoded by genes that are conserved from yeast to humans. Mutations with interesting developmental phenotypes have been identified in Caenorhabditis elegans, Drosophila and mouse. It is hypothesized that these bifunctional proteins provide a rich source of interesting molecular information about development and define a new cellular pathway that links signal transduction directly to RNA metabolism.

MeSH Terms
Amino Acid Sequence Animals Caenorhabditis elegans/genetics Caenorhabditis elegans Proteins DNA-Binding Proteins/genetics,metabolism Drosophila Proteins Helminth Proteins/genetics Mice Mice, Mutant Strains Molecular Sequence Data Mutation Nuclear Proteins Phosphoproteins/genetics,metabolism RNA/metabolism RNA Splicing Factors RNA-Binding Proteins/genetics,metabolism Sequence Homology, Amino Acid Signal Transduction Transcription Factors
Chemicals
Caenorhabditis elegans Proteins DNA-Binding Proteins DOK1 protein, human Dok1 protein, mouse Drosophila Proteins GAP-associated protein p62 GLD-1 protein, C elegans Helminth Proteins Nuclear Proteins Phosphoproteins QKI protein, human Qk protein, mouse RNA Splicing Factors RNA-Binding Proteins SF1 protein, Drosophila Sf1 protein, mouse Transcription Factors how protein, Drosophila sfa-1 protein, C elegans RNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Vernet C
Cell and Molecular Biology Institute, University of Texas at Austin 78712-1064, USA. vernet@uts.cc.utexas.edu
Artzt K
Article Info
Journal
Trends in genetics : TIG
Abbr.
Trends Genet
ISSN
0168-9525
Published
1997-12-00
Pages
479-84
Language
English
Region
England
NLM ID
8507085
Subset
IM
Grants
NICHD NIH HHS · HD10668 · United States
NICHD NIH HHS · HD30658 · United States
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com