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PMID: 940740 Published · ppublish fre Case Reports English Abstract Journal Article

[Angioimmunoblastic adenopathies].

Les adénopathies angio-immunoblastiques

La Nouvelle presse medicale ·Vol. 5 ·No. 24 ·1976-06-12 ·Pages 1515-8

Mathé G, Amiel JL, Gérard-Marchant R, Caillou B, Pico JL, Machover D

Abstract

Angio-lymphoblastic lymphadenopathies are a newly described haematological entity, though not rare, characterised by a histological triad (vascular neogenesis, highly polymorphic or predominantly immunoblastic cellular proliferation and the presence of acidophilic protein deposits), a clinical syndrome consisting essentially of voluminous disseminated lymphadenopathy and hepatosplenomegaly and abnormal laboratory findings dominated by a polyclonal dysproteinaemia. This disorder, the first four French cases of which are described here, does not appear to be malignant in its early stages and is sensitive to corticosteroid therapy at that time. Secondary sarcomatous transformation is possible.

MeSH Terms
Adult Aged Cell Transformation, Neoplastic Diagnosis, Differential Dysgammaglobulinemia/diagnosis,immunology,pathology Female Hepatomegaly/etiology Humans Hypergammaglobulinemia/diagnosis,immunology,pathology Immunologic Deficiency Syndromes/immunology Lymph Nodes/pathology Lymphatic Diseases/diagnosis,immunology,pathology Male Middle Aged Sarcoma/diagnosis Splenomegaly/etiology
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Mathé G
Amiel J L
Gérard-Marchant R
Caillou B
Pico J L
Machover D
Article Info
Journal
La Nouvelle presse medicale
Abbr.
Nouv Presse Med
ISSN
0301-1518
Published
1976-06-12
Pages
1515-8
Language
fre
Region
France
NLM ID
0312552
Subset
IM
External Links
PubMed source
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