Two cases of trisomy 4p with translocation t(4p-,7q+) in several members of one family.

Human genetics ·Vol. 33 ·No. 2 ·1976-07-27 ·Pages 155-60

Andrle M, Erlach A, Killian W, Rett A

Abstract

Report of a family with 7 cases of balanced translocation t(4p-,7q+), resulting in partial trisomy in 2 children descending from parents being brother and sister. Description of the clinical cases, family history, and cytogenetic findings followed by a short discussion of phenotypical differences of the two probands.

MeSH Terms

Adolescent Chromosome Aberrations Chromosomes, Human, 4-5 Chromosomes, Human, 6-12 and X Face Female Humans Male Pedigree Phenotype Translocation, Genetic Trisomy

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Andrle M

Erlach A

Killian W

Rett A

References (6)

6 references, click to expand

The 4p-syndrome, with a report of two new cases.
Humangenetik. 1973;19(1):99-109 PMID: 4725911
Trisomy 4p14 leads to 4pter with translocation t(4;15)(p14;p12) in the father.
Humangenetik. 1975 Oct 7;29(4):329-35 PMID: 1176148
The use of proteolytic enzymes for the mapping of structural rearrangements in the chromosomes of man.
Chromosoma. 1972;36(2):204-10 PMID: 5016007
[Partial trisomy for the short arm of chromosome 4 with translocation 4p-,18q+ in the father].
Humangenetik. 1972;15(2):163-71 PMID: 5049069
[Trisomy 4p].
Ann Genet. 1974 Jun;17(2):125-8 PMID: 4547940
[Trisomy 4p. Three new observations (author's transl)].
Humangenetik. 1975 Nov 6;30(2):99-108 PMID: 1193607

Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00281889

Published

1976-07-27

Pages

155-60

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00281889 View journal details

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Two cases of trisomy 4p with translocation t(4p-,7q+) in several members of one family.

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