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PMID: 9352942 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

SigmaE is an essential sigma factor in Escherichia coli.

Journal of bacteriology ·Vol. 179 ·No. 21 ·1997-11-00 ·Pages 6862-4

De Las Peñas A, Connolly L, Gross CA

Abstract

SigmaE is an alternative sigma factor that controls the extracytoplasmic stress response in Escherichia coli. SigmaE is essential at high temperatures but was previously thought to be nonessential at temperatures below 37 degrees C. We present evidence that sigmaE is an essential sigma factor at all temperatures. Cells lacking sigmaE are able to grow at low temperatures because of the presence of a frequently arising, unlinked suppressor mutation.

MeSH Terms
Escherichia coli/genetics,growth & development Mutagenesis Recombinant Proteins/biosynthesis Sigma Factor/antagonists & inhibitors,genetics,metabolism Suppression, Genetic Temperature Transcription Factors/antagonists & inhibitors,genetics,metabolism Transduction, Genetic
Chemicals
Recombinant Proteins Sigma Factor Transcription Factors sporulation-specific sigma factors
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
De Las Peñas A
Department of Bacteriology, University of Wisconsin-Madison, 53706, USA.
Connolly L
Gross C A
References (17)
17 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.179.21.6862-6864.1997
Published
1997-11-00
Pages
6862-4
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC179621
Subset
IM
Grants
NIGMS NIH HHS · GM07618 · United States
NIGMS NIH HHS · GM36278 · United States
External Links
PubMed source DOI: 10.1128/jb.179.21.6862-6864.1997 PMC Full Text View journal details
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