Glial cell extracellular matrix: boundaries for axon growth in development and regeneration.

Cell and tissue research ·Vol. 290 ·No. 2 ·1997-11-00 ·Pages 379-84

Fitch MT, Silver J

Abstract

Astrocytes and other glia in the central nervous system are now thought to produce molecules that negatively modulate axon growth, thereby influencing axon pathfinding in both development and regeneration. The relevant evidence for glial cell boundaries and the inhibitory molecules present in these extracellular matrix structures is discussed in this minireview.

MeSH Terms

Animals Axons/physiology Extracellular Matrix/physiology Humans Nerve Regeneration Nervous System/embryology Nervous System Physiological Phenomena Neuroglia/physiology Neurons/physiology

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fitch M T

Department of Neurosciences, Case Western Reserve University School of Medicine, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA. mtf@po.cwru.edu

Silver J

Article Info

Journal

Cell and tissue research

Abbr.

Cell Tissue Res

ISSN

0302-766X

DOI

10.1007/s004410050944

mtf@po.cwru.edu

Published

1997-11-00

Pages

379-84

Language

English

Region

Germany

NLM ID

0417625

Subset

External Links

PubMed source DOI: 10.1007/s004410050944 View journal details

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Glial cell extracellular matrix: boundaries for axon growth in development and regeneration.

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