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题目:: The sidekick gene, a member of the immunoglobulin superfamily, is required for pattern formation in the Drosophila eye.
作者:: Nguyen(D N),Liu(Y),Litsky(M L),Reinke(R)
状态:: 发布时间1997-10-28 , 更新时间 2008-11-21
期刊:: Development
摘要:: In the Drosophila eye imaginal disc the photoreceptor cells (R cells) differentiate according to a precise spatial and temporal order. The sidekick (sdk) gene is necessary to prevent extra R cells from differentiating during eye disc development. The extra cell appears between R3 and R4 early in R cell clusters and is most likely the result of the mystery cell inappropriately differentiating as an R cell. Mosaic analysis shows that sdk is required neither in the R cells nor in the extra cell, suggesting that sdk is necessary in the surrounding undifferentiated cells. The sdk gene codes for a protein that is a member of the immunoglobulin superfamily, having six immunoglobulin domains, thirteen fibronectin repeats and a transmembrane domain. The protein structure is consistent with its participation in cell-cell interaction during eye development.
语言:: eng
DOI:

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