An inverse mammalian two-hybrid system for beta secretase and other proteases.

Amyloid Precursor Protein Secretases Amyloid beta-Protein Precursor/genetics Aspartic Acid Endopeptidases Binding Sites/genetics Blotting, Western Cell Line Chloramphenicol O-Acetyltransferase/genetics Endopeptidases/genetics Enzyme Activation/genetics Gene Expression Regulation Humans Plasmids/chemistry Polymerase Chain Reaction Recombinant Fusion Proteins/chemistry Substrate Specificity Transfection

Amyloid beta-Protein Precursor Recombinant Fusion Proteins Chloramphenicol O-Acetyltransferase Amyloid Precursor Protein Secretases Endopeptidases Aspartic Acid Endopeptidases BACE1 protein, human