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PMID: 9204706 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Transporters of nucleotide sugars, nucleotide sulfate and ATP in the Golgi apparatus.

Trends in biochemical sciences ·Vol. 22 ·No. 6 ·1997-06-00 ·Pages 203-7

Abeijon C, Mandon EC, Hirschberg CB

Abstract

Proteins and glycolipids are glycosylated, sulfated and phosphorylated in the lumen of the Golgi apparatus. The nucleotide substrates of these reactions must first be translocated from the cytosol into the Golgi lumen by specific transporters (antiporters). These are hydrophobic, transmembrane spanning proteins that appear to regulate post-translational modifications in the Golgi lumen.

MeSH Terms
Adenosine Triphosphate/metabolism Animals Antiporters/chemistry,metabolism Biological Transport Carbohydrate Metabolism Endoplasmic Reticulum/metabolism Glycosylation Golgi Apparatus/metabolism Mutation Nucleotides/metabolism Phosphorylation Sulfates/metabolism
Chemicals
Antiporters Nucleotides Sulfates Adenosine Triphosphate
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Abeijon C
Department of Biochemistry and Molecular Biology, University of Massachusetts Medical Center, Worcester 01655, USA.
Mandon E C
Hirschberg C B
Article Info
Journal
Trends in biochemical sciences
Abbr.
Trends Biochem Sci
ISSN
0968-0004
Published
1997-06-00
Pages
203-7
Language
English
Region
England
NLM ID
7610674
Subset
IM
Grants
PHS HHS · R01-34396 · United States
PHS HHS · R37-30365 · United States
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