Home LiteratureArticle Details
PMID: 9150173 Published · ppublish English Letter Research Support, Non-U.S. Gov't

Frequently occurring germ-line mutations of the BRCA1 gene in ovarian cancer families from Russia.

American journal of human genetics ·Vol. 60 ·No. 5 ·1997-05-00 ·Pages 1239-42

Gayther SA, Harrington P, Russell P, Kharkevich G, Garkavtseva RF, Ponder BA

Abstract

暂无摘要

MeSH Terms
Breast Neoplasms/epidemiology,genetics Ethnicity/genetics Female Gene Frequency Genes, BRCA1/genetics Humans Microsatellite Repeats Middle Aged Mutation Ovarian Neoplasms/epidemiology,genetics Polymorphism, Single-Stranded Conformational Russia/epidemiology Sequence Analysis, DNA
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Gayther S A
Harrington P
Russell P
Kharkevich G
Garkavtseva R F
Ponder B A
References (18)
18 references, click to expand
  1. A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
    Science. 1994 Oct 7;266(5182):66-71 PMID: 7545954
  2. Familial site-specific ovarian cancer is linked to BRCA1 on 17q12-21.
    Am J Hum Genet. 1994 Nov;55(5):870-5 PMID: 7977348
  3. Breast and ovarian cancer incidence in BRCA1-mutation carriers. Breast Cancer Linkage Consortium.
    Am J Hum Genet. 1995 Jan;56(1):265-71 PMID: 7825587
  4. The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals.
    Nat Genet. 1995 Oct;11(2):198-200 PMID: 7550349
  5. Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.
    Nat Genet. 1995 Dec;11(4):428-33 PMID: 7493024
  6. Germ-line BRCA1 mutations in Jewish and non-Jewish women with early-onset breast cancer.
    N Engl J Med. 1996 Jan 18;334(3):143-9 PMID: 8531968
  7. Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families: results of an international study.
    Am J Hum Genet. 1996 Feb;58(2):271-80 PMID: 8571953
  8. Growth retardation and tumour inhibition by BRCA1.
    Nat Genet. 1996 Mar;12(3):298-302 PMID: 8589721
  9. Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.
    Am J Hum Genet. 1993 Apr;52(4):678-701 PMID: 8460634
  10. Ovarian cancer risk in BRCA1 carriers is modified by the HRAS1 variable number of tandem repeat (VNTR) locus.
    Nat Genet. 1996 Mar;12(3):309-11 PMID: 8589723
  11. Mouse Brca1: localization sequence analysis and identification of evolutionarily conserved domains.
    Hum Mol Genet. 1995 Dec;4(12):2265-73 PMID: 8634697
  12. Murine Brca1: sequence and significance for human missense mutations.
    Hum Mol Genet. 1995 Dec;4(12):2275-8 PMID: 8634698
  13. Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis. UKCCCR Familial Ovarian Cancer Study Group.
    Am J Hum Genet. 1996 Mar;58(3):451-6 PMID: 8644703
  14. Transcriptional activation by BRCA1.
    Nature. 1996 Aug 22;382(6593):678-9 PMID: 8751436
  15. Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene. Breast Cancer Information Core.
    Hum Mutat. 1996;8(1):8-18 PMID: 8807330
  16. Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2.
    Nat Genet. 1996 Oct;14(2):185-7 PMID: 8841191
  17. Mutation analysis of BRCA1 and BRCA2 in a male breast cancer population.
    Am J Hum Genet. 1997 Feb;60(2):313-9 PMID: 9012404
  18. Analysis of BRCA1 and BRCA2 mutations in Hungarian families with breast or breast-ovarian cancer.
    Am J Hum Genet. 1997 May;60(5):1242-6 PMID: 9150174
Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1997-05-00
Pages
1239-42
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1712436
Subset
IM
Corrections
CommentIn
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com