Genes involved in T-cell receptor-mediated apoptosis of thymocytes and T-cell hybridomas.
作者:
Winoto(A)
状态:
发布时间1997-07-24
, 更新时间 2009-11-19
期刊:
Semin Immunol
摘要:
Stimulation of the T-cell receptor complex in resting T cells leads to activation. However, antigenic stimulation of immature T lymphocytes and activated mature T cells results in apoptosis. Recent work suggests that distinct signaling pathways in T cells mediate cell death and cell activation. In this article, genes that are involved in apoptosis of immature T cells and T-cell hybridomas are discussed.