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PMID: 9105849 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Distinct genotypic clusters of heterogeneously and homogeneously methicillin-resistant Staphylococcus aureus from a Greek hospital.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology ·Vol. 16 ·No. 2 ·1997-02-00 ·Pages 170-3

Tassios PT, Vatopoulos AC, Xanthaki A, Mainas E, Goering RV, Legakis NJ

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) strains isolated over a one-year period from a Greek hospital were tested for their levels of resistance to methicillin by population analysis. Heterogeneously resistant strains belonged to classes I, II, and II/III, whereas homogeneously resistant ones belonged to class IV. Strains of all classes possessed the mecA gene. Pulsed-field gel electrophoresis (PFGE) of Smal-digested genomic DNA revealed that all heterogeneously resistant strains were also closely related, but in a cluster distinct from the heterogeneous one. The methicillin-sensitive strains displayed a greater variety of PFGE types compared to MRSA isolates.

MeSH Terms
Bacterial Proteins/genetics Electrophoresis, Gel, Pulsed-Field Humans Methicillin Resistance/genetics Polymorphism, Genetic Staphylococcal Infections/drug therapy Staphylococcus aureus/classification,drug effects,genetics
Chemicals
Bacterial Proteins
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Tassios P T
Department of Microbiology, Medical School, National University of Athens, Greece.
Vatopoulos A C
Xanthaki A
Mainas E
Goering R V
Legakis N J
References (12)
12 references, click to expand
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Article Info
Journal
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology
Abbr.
Eur J Clin Microbiol Infect Dis
ISSN
0934-9723
DOI
10.1007/BF01709481
Published
1997-02-00
Pages
170-3
Language
English
Region
Germany
NLM ID
8804297
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01709481 View journal details
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