Histone acetyltransferases in control.

Current biology : CB ·Vol. 7 ·No. 2 ·1997-02-01 ·Pages R82-4

Wade PA, Wolffe AP

Abstract

Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.

MeSH Terms

Acetyltransferases/metabolism Animals Chromatin/physiology Gene Expression Regulation Histone Acetyltransferases Histone Deacetylases/metabolism Models, Biological Saccharomyces cerevisiae/metabolism Saccharomyces cerevisiae Proteins Transcription, Genetic Transcriptional Activation

Chemicals

Chromatin Saccharomyces cerevisiae Proteins Acetyltransferases Histone Acetyltransferases Histone Deacetylases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Wade P A

Laboratory of Molecular Embryology, NICHHD, Bethesda, Maryland, 20892-5431, USA. awlme@helix.nih.gov

Wolffe A P

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(06)00042-x

awlme@helix.nih.gov

Published

1997-02-01

Pages

R82-4

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(06)00042-x View journal details

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