TNP-470 (AGM-1470): mechanisms of action and early clinical development.

Animals Antibiotics, Antineoplastic/adverse effects,pharmacology,therapeutic use Cattle Cells, Cultured Clinical Trials as Topic Combined Modality Therapy Cyclohexanes Drug Therapy, Combination Endothelium, Vascular/drug effects Humans Macaca mulatta Mice Neoplasms/drug therapy Neovascularization, Pathologic/drug therapy Neovascularization, Physiologic/drug effects O-(Chloroacetylcarbamoyl)fumagillol Rats Sesquiterpenes/adverse effects,pharmacology,therapeutic use

Antibiotics, Antineoplastic Cyclohexanes Sesquiterpenes O-(Chloroacetylcarbamoyl)fumagillol