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PMID: 9047354 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

misshapen encodes a protein kinase involved in cell shape control in Drosophila.

Gene ·Vol. 186 ·No. 1 ·1997-02-20 ·Pages 119-25

Treisman JE, Ito N, Rubin GM

Abstract

We have identified a novel protein kinase encoded by the misshapen gene, which is required for the normal shape and orientation of Drosophila photoreceptor cells. misshapen is also expressed in the embryonic mesoderm, pole plasm and other sites of cell shape change or movement. We propose that msn may act in a signal transduction pathway leading to cytoskeletal re-arrangements.

MeSH Terms

Amino Acid Sequence Animals Cell Movement/genetics Drosophila/embryology,genetics Embryo, Nonmammalian/cytology Embryonic and Fetal Development/genetics Eye/embryology,pathology Gene Expression Regulation, Developmental Molecular Sequence Data Photoreceptor Cells, Invertebrate/pathology Protein Kinases/biosynthesis,genetics,physiology Sequence Analysis, DNA Sequence Homology, Amino Acid Transcription, Genetic

Chemicals

Protein Kinases

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Treisman J E

MCB and HHMI, University of California at Berkeley 94704, USA. treisman@saturn.med.nyu.edu

Ito N

Rubin G M

Article Info

Journal

Gene

Abbr.

Gene

ISSN

0378-1119

DOI

10.1016/s0378-1119(96)00694-4

treisman@saturn.med.nyu.edu

Published

1997-02-20

Pages

119-25

Language

English

Region

Netherlands

NLM ID

7706761

Subset

Grants

NIGMS NIH HHS · GM33135 · United States

External Links

PubMed source DOI: 10.1016/s0378-1119(96)00694-4 View journal details

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misshapen encodes a protein kinase involved in cell shape control in Drosophila.

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