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PMID: 8961482 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Reversible deactivation of cerebral network components.

Trends in neurosciences ·Vol. 19 ·No. 12 ·1996-12-00 ·Pages 535-42

Payne BR, Lomber SG, Villa AE, Bullier J

Abstract

Reversible deactivation techniques have shown that the cerebral network: (1) is dynamic, its functions depending on contemporaneous processing elsewhere in the network; (2) is composed of single nodes that contribute to several behaviors; (3) possesses an inherent plasticity that tends to minimize lesion-induced deficits; and (4) comprises feedforward and lateral connections that contribute in different ways to network operations. The next major advances in understanding network operations will probably be made by applying a combination of behavioral, neuron-recording and deactivation techniques. The greatest near-term gains are likely to be made in understanding the contributions that feedback projections make to cerebral network function.

MeSH Terms
Animals Cerebral Cortex/physiology Neural Pathways/physiology
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Payne B R
Dept of Anatomy and Neurobiology, Boston University School of Medicine, MA 02118, USA.
Lomber S G
Villa A E
Bullier J
Article Info
Journal
Trends in neurosciences
Abbr.
Trends Neurosci
ISSN
0166-2236
Published
1996-12-00
Pages
535-42
Language
English
Region
England
NLM ID
7808616
Subset
IM
Corrections
CommentIn
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