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题目:: RtoA links initial cell type choice to the cell cycle in Dictyostelium.
作者:: Wood(S A),Ammann(R R),Brock(D A),Li(L),Spann(T),Gomer(R H)
状态:: 发布时间1997-01-23 , 更新时间 2005-11-17
期刊:: Development
摘要:: In Dictyostelium, initial cell type choice is correlated with the cell-cycle phase of the cell at the time of starvation. We have isolated a mutant, ratioA (rtoA), with a defect in this mechanism that results in an abnormally high percentage of prestalk cells. The rtoA gene has been cloned and sequenced and codes for a novel protein. The cell cycle is normal in rtoA. In the wild type, prestalk cells differentiate from those cells in S or early G2 phase at starvation and prespore cells from cells in late G2 or M phase at starvation. In rtoA mutants, both prestalk and prespore cells originate randomly from cells in any phase of the cell cycle at starvation.
语言:: eng
DOI:

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