The effect of 4-amino hex-5-ynoic acid (gamma-acetylenic GABA, gammma-ethynyl GABA) a catalytic inhibitor of GABA transaminase, on brain GABA metabolism in vivo.

Journal of neurochemistry ·Vol. 28 ·No. 4 ·1977-04-00 ·Pages 717-23

Jung MJ, Lippert B, Metcalf BW, Schechter PJ, Böhlen P, Sjoerdsma A

Abstract

暂无摘要

MeSH Terms

4-Aminobutyrate Transaminase/antagonists & inhibitors Alanine Transaminase/metabolism Aminobutyrates/analogs & derivatives Animals Aspartate Aminotransferases/metabolism Brain/drug effects,enzymology Dose-Response Relationship, Drug Glutamate Decarboxylase/metabolism Mice Rats Transaminases/antagonists & inhibitors gamma-Aminobutyric Acid/analogs & derivatives,metabolism,pharmacology

Chemicals

Aminobutyrates gamma-Aminobutyric Acid Transaminases Aspartate Aminotransferases 4-Aminobutyrate Transaminase Alanine Transaminase Glutamate Decarboxylase

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Jung M J

Lippert B

Metcalf B W

Schechter P J

Böhlen P

Sjoerdsma A

Article Info

Journal

Journal of neurochemistry

Abbr.

J Neurochem

ISSN

0022-3042

DOI

10.1111/j.1471-4159.1977.tb10618.x

Published

1977-04-00

Pages

717-23

Language

English

Region

England

NLM ID

2985190R

Subset

External Links

PubMed source DOI: 10.1111/j.1471-4159.1977.tb10618.x View journal details

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The effect of 4-amino hex-5-ynoic acid (gamma-acetylenic GABA, gammma-ethynyl GABA) a catalytic inhibitor of GABA transaminase, on brain GABA metabolism in vivo.

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