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PMID: 887941 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs.

Science (New York, N.Y.) ·Vol. 197 ·No. 4308 ·1977-09-09 ·Pages 1092-4

Kaplan MS, Hinds JW

Abstract

Three-month-old rats were injected intraperitoneally with [3H]thymidine (4.3 microcuries per gram of body weight) and allowed to survive for 30 days. Radioautography of 1-micrometer sections revealed labeled cells in the granular layers of dentate gyrus and olfactory bulb; these were confirmed as neurons by electron microscopy of reembedded 1-micrometer sections.

MeSH Terms

Age Factors Animals Hippocampus/cytology,growth & development,metabolism Male Neurons/metabolism,physiology Olfactory Bulb/cytology,growth & development,metabolism Rats Thymidine/metabolism

Chemicals

Thymidine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kaplan M S

Hinds J W

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.887941

Published

1977-09-09

Pages

1092-4

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.887941 View journal details

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Neurogenesis in the adult rat: electron microscopic analysis of light radioautographs.

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