RNA splicing: unexpected spliceosome diversity.

Current biology : CB ·Vol. 6 ·No. 7 ·1996-07-01 ·Pages 802-5

Kreivi JP, Lamond AI

Abstract

A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution and expression of eukaryotic genes.

MeSH Terms

Animals Humans Introns Nuclear Proteins/genetics RNA Precursors RNA Splicing Ribonucleoproteins, Small Nuclear/metabolism Spliceosomes tRNA Methyltransferases

Chemicals

Nuclear Proteins RNA Precursors Ribonucleoproteins, Small Nuclear U11 small nuclear ribonucleoprotein, human U11-U12 small nuclear ribonucleoprotein NOP2 protein, human tRNA Methyltransferases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Kreivi J P

Department of Biochemistry, University of Dundee, Scotland, UK.

Lamond A I

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(02)00599-7

Published

1996-07-01

Pages

802-5

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(02)00599-7 View journal details

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