A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15.

Pharmacogenetics ·Vol. 6 ·No. 3 ·1996-06-00 ·Pages 269-72

Sachse C, Brockmöller J, Bauer S, Reum T, Roots I

Abstract

暂无摘要

MeSH Terms

Adult Alleles Cytochrome P-450 CYP2D6/genetics,metabolism Debrisoquin/pharmacokinetics,urine Dextromethorphan/pharmacokinetics,urine Exons Frameshift Mutation Humans Male Phenotype Pseudogenes

Chemicals

Dextromethorphan Cytochrome P-450 CYP2D6 Debrisoquin

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Sachse C

Institut für Klinische Pharmakologie, Universitätsklinikum Charité der Humboldt-Universitätzn Berlin, Germany.

Brockmöller J

Bauer S

Reum T

Roots I

Article Info

Journal

Pharmacogenetics

Abbr.

Pharmacogenetics

ISSN

0960-314X

DOI

10.1097/00008571-199606000-00012

Published

1996-06-00

Pages

269-72

Language

English

Region

England

NLM ID

9211735

Subset

External Links

PubMed source DOI: 10.1097/00008571-199606000-00012

Analysis Services

A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15.

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