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PMID: 8807079 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Novel method for assessing postantibiotic effect by using the Coulter counter.

Antimicrobial agents and chemotherapy ·Vol. 40 ·No. 7 ·1996-07-00 ·Pages 1751-3

Li RC, Lee SW, Lam JS

Abstract

To study postantibiotic effect, viable counts are routinely acquired by the pour plate technique. However, this technique is laborious and time-consuming; the required sample dilutions also cause excessive errors and material wastage. A new total cell counting technique in which a Coulter counter is used to obtain more efficient postantibiotic effect measurements has been developed.

MeSH Terms
Anti-Bacterial Agents/pharmacology Bacteriological Techniques Enterococcus faecalis/drug effects,growth & development Escherichia coli/drug effects,growth & development Staphylococcus aureus/drug effects,growth & development Substance Withdrawal Syndrome
Chemicals
Anti-Bacterial Agents
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Li R C
Department of Pharmacy, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong.
Lee S W
Lam J S
References (10)
10 references, click to expand
  1. Kinetics and mechanisms of action of drugs on microorganisms. XV. Effect of erythromycin on the action of lincomycin (Phase II) and the 7 (S)-chloro analogs of lincomycin against Escherichia coli.
    J Pharm Sci. 1972 Apr;61(4):545-51 PMID: 4552281
  2. Kinetics and mechanisms of drug action on microorganisms. 13. Comparative studies on action of lincomycin, clindamycin, and U 24729A against Escherichia coli.
    J Med Chem. 1972 Feb;15(2):152-63 PMID: 4550331
  3. Kinetics and mechanisms of action of drugs on microorganisms. VII. Quantitative adherence of sulfonamide action on microbial growth to a receptor-site model.
    J Pharm Sci. 1967 Dec;56(12):1576-85 PMID: 4871916
  4. Quantitation of postantibiotic effect by measuring CO2 generation of bacteria with the BACTEC blood culture system.
    Antimicrob Agents Chemother. 1991 Dec;35(12):2658-61 PMID: 1810205
  5. Postantibiotic effects.
    J Antimicrob Chemother. 1985 Jan;15 Suppl A:37-46 PMID: 3980335
  6. The postantibiotic effect: a review of in vitro and in vivo data.
    DICP. 1991 Feb;25(2):153-63 PMID: 2058187
  7. Comparison of electronic and viability counting methods for determination of postantibiotic effect of oxacillin on Staphylococcus aureus.
    Antimicrob Agents Chemother. 1989 Dec;33(12):2155-6 PMID: 2694953
  8. Postantibiotic effect of aminoglycosides on gram-negative bacteria evaluated by a new method.
    J Antimicrob Chemother. 1988 Jul;22(1):23-33 PMID: 3139614
  9. Kinetics and mechanisms of action of antibiotics on microorganisms. V. Chloramphenicol and tetracycline affected Escherichia coli generation rates.
    J Pharm Sci. 1966 Jun;55(6):593-600 PMID: 5332367
  10. Comparison of two methods for determining in vitro postantibiotic effects of three antibiotics on Escherichia coli.
    Antimicrob Agents Chemother. 1988 Apr;32(4):450-3 PMID: 3288112
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.40.7.1751
Published
1996-07-00
Pages
1751-3
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC163412
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.40.7.1751 PMC Full Text View journal details
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