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PMID: 8755036 Published · ppublish rus English Abstract Journal Article Research Support, Non-U.S. Gov't

[Cloning of the tag7 gene expressed in metastatic mouse tumors].

Klonirovanie gena tag7, ékspressiruiushchegosia v v metastaziruiushchikh opukholiakh myshi.

Genetika ·Vol. 32 ·No. 5 ·1996-05-00 ·Pages 621-8

Kustikova OS, Kiselev SL, Borodulina OR, Senin VM, Afanas'eva AV, Kabishev AA

Abstract

Gene expression was compared in a metastatic (VMR-Liv) neoplastic cell line and a related nonmetastatic (VMR-O) neoplastic cell line by means of the differential display method. A fragment of cDNA corresponding to the tag7 gene, differentially expressed in the metastatic cell line, was isolated. The full-length tag7 cDNA was cloned and its nucleotide sequence was determined. No homology between the tag7 gene and known sequences was revealed. tag7 gene transcription was studied in some tumors, cell lines, and normal mouse organs.

MeSH Terms

Amino Acid Sequence Animals Base Sequence Cell Line Cloning, Molecular Gene Expression Regulation, Neoplastic/physiology Mice Mice, Inbred A Molecular Sequence Data Neoplasm Metastasis Oncogenes Polymerase Chain Reaction/methods Reference Values Sequence Analysis, DNA/methods Transcription, Genetic Tumor Cells, Cultured

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Kustikova O S

Kiselev S L

Borodulina O R

Senin V M

Afanas'eva A V

Kabishev A A

Article Info

Journal

Genetika

Abbr.

Genetika

ISSN

0016-6758

Published

1996-05-00

Pages

621-8

Language

rus

Region

Russia (Federation)

NLM ID

0047354

Subset

Databases

GENBANK

X86374

External Links

PubMed source

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[Cloning of the tag7 gene expressed in metastatic mouse tumors].

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