Apoptosis of lymphocytes in mice induced by infection with Rickettsia tsutsugamushi.

Infection and immunity ·Vol. 64 ·No. 9 ·1996-09-00 ·Pages 3937-41

Kasuya S, Nagano I, Ikeda T, Goto C, Shimokawa K, Takahashi Y

Abstract

Histological examinations of mice infected with either a lethal (Karp) or a self-limitating (Gilliam) strain of Rickettsia tsutsugamushi were performed. Tingible body macrophages in the spleen and necrotizing lymphadenitis in regional lymph nodes were prominent only in the former. Apoptotic legions in the lymphocytes of these organs were clearly demonstrated by histochemical and electron microscopical examinations.

MeSH Terms

Animals Apoptosis DNA/chemistry Lymph Nodes/cytology Lymphocytes/cytology Macrophages/cytology Mice Mice, Inbred BALB C Microscopy, Electron Orientia tsutsugamushi/immunology Scrub Typhus/immunology,pathology Spleen/cytology

Chemicals

DNA

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Kasuya S

Department of Parasitology, Gifu University School of Medicine, Japan.

Nagano I

Ikeda T

Goto C

Shimokawa K

Takahashi Y

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Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.64.9.3937-3941.1996

Published

1996-09-00

Pages

3937-41

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC174319

Subset

External Links

PubMed source DOI: 10.1128/iai.64.9.3937-3941.1996 PMC Full Text View journal details

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Apoptosis of lymphocytes in mice induced by infection with Rickettsia tsutsugamushi.

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