WW domains.

Structure (London, England : 1993) ·Vol. 4 ·No. 5 ·1996-05-15 ·Pages 495-9

Staub O, Rotin D

Abstract

WW domains are recently described protein-protein interaction modules; they bind to proline-rich sequences that usually also contain a tyrosine. These domains have been detected in several unrelated proteins, often alongside other domains. Recent studies suggest that WW domains in specific proteins may play a role in diseases such as hypertension or muscular dystrophy.

MeSH Terms

Amino Acid Sequence Animals Consensus Sequence Dystrophin/genetics,physiology Humans Models, Chemical Molecular Sequence Data Proline/chemistry Protein Binding Proteins/chemistry Sequence Alignment Sequence Homology, Amino Acid Tyrosine/chemistry

Chemicals

Dystrophin Proteins Tyrosine Proline

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Staub O

Hospital For Sick Children, Division of Respiratory Research, Toronto, Ontario, Canada.

Rotin D

Article Info

Journal

Structure (London, England : 1993)

Abbr.

Structure

ISSN

0969-2126

DOI

10.1016/s0969-2126(96)00054-8

Published

1996-05-15

Pages

495-9

Language

English

Region

United States

NLM ID

101087697

Subset

External Links

PubMed source DOI: 10.1016/s0969-2126(96)00054-8 View journal details

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