Mechanisms involved in the generation of free radicals.

Pathologie-biologie ·Vol. 44 ·No. 1 ·1996-01-00 ·Pages 6-13

Halliwell B

Abstract

Free radicals are constantly formed in the human body, both by "accidents of chemistry" and for useful metabolic purposes. Their action is opposed by a balanced and co-ordinated system of antioxidant defences. Upsetting this balance causes oxidative stress, which can lead to cell injury and death.

MeSH Terms

Humans Hydrogen Peroxide/metabolism,toxicity Hydroxyl Radical/metabolism Nitric Oxide/metabolism,toxicity Oxidants/metabolism Oxidative Stress/physiology Superoxide Dismutase/metabolism Superoxides/metabolism,toxicity

Chemicals

Oxidants Superoxides Nitric Oxide Hydroxyl Radical Hydrogen Peroxide Superoxide Dismutase

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Halliwell B

Pharmacology Group, University of London King's College.

Article Info

Journal

Pathologie-biologie

Abbr.

Pathol Biol (Paris)

ISSN

0369-8114

Published

1996-01-00

Pages

6-13

Language

English

Region

France

NLM ID

0265365

Subset

External Links

PubMed source View journal details

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Mechanisms involved in the generation of free radicals.

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