Home LiteratureArticle Details

PMID: 8648752 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Inactivated bovine herpesvirus 1 induces apoptotic cell death of mitogen-stimulated bovine peripheral blood mononuclear cells.

Journal of virology ·Vol. 70 ·No. 6 ·1996-06-00 ·Pages 4116-20

Hanon E, Vanderplasschen A, Lyaku S, Keil G, Denis M, Pastoret PP

Abstract

Bovine herpesvirus 1 (BHV-1) is able to inhibit the proliferation of bovine peripheral blood mononuclear cells. Here, we have demonstrated that live BHV-1 and, interestingly, inactivated BHV-1 can induce apoptosis of mitogen-stimulated bovine peripheral blood mononuclear cells in vitro.

MeSH Terms

Animals Apoptosis Cattle Cells, Cultured DNA/metabolism Herpesvirus 1, Bovine/physiology Ionomycin/pharmacology Leukocytes, Mononuclear/pathology Phorbol 12,13-Dibutyrate/pharmacology Viral Proteins/analysis

Chemicals

Viral Proteins Phorbol 12,13-Dibutyrate Ionomycin DNA

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Hanon E

Department of Immunology/Vaccinology, Faculty of Veterinary Medicine, University of Liège, Belgium. hanon@stat.fmv.ulg.ac.be

Vanderplasschen A

Lyaku S

Keil G

Denis M

Pastoret P P

References (29)

29 references, click to expand

A review of infectious bovine rhinotracheitis, shipping fever pneumonia and viral-bacterial synergism in respiratory disease of cattle.
Can J Comp Med. 1982 Jul;46(3):225-63 PMID: 6290011
Microplitis demolitor polydnavirus induces apoptosis of a specific haemocyte morphotype in Pseudoplusia includens.
J Gen Virol. 1995 Feb;76 ( Pt 2):283-91 PMID: 7844550
Viral-bacterial pneumonia in calves: effect of bovine herpesvirus-1 on immunologic functions.
J Infect Dis. 1985 May;151(5):937-47 PMID: 2580916
Viruses perturb lymphocyte functions: selected principles characterizing virus-induced immunosuppression.
Annu Rev Immunol. 1987;5:279-304 PMID: 3036182
Fluorescence-activated cell analysis and sorting of viable mammalian cells based on beta-D-galactosidase activity after transduction of Escherichia coli lacZ.
Proc Natl Acad Sci U S A. 1988 Apr;85(8):2603-7 PMID: 3128790
Inhibition of T-lymphocyte mitogenic responses and effects on cell functions by bovine herpesvirus 1.
J Virol. 1989 Apr;63(4):1525-30 PMID: 2538643
The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes.
J Gen Virol. 1990 Feb;71 ( Pt 2):369-77 PMID: 2155290
Apoptosis. The role of the endonuclease.
Am J Pathol. 1990 Mar;136(3):593-608 PMID: 2156431
Inhibition of antigen-induced and interleukin-2-induced proliferation of bovine peripheral blood leukocytes by inactivated bovine herpes virus 1.
J Virol. 1990 Sep;64(9):4146-51 PMID: 2166810
Identification and characterization of a novel non-infectious herpes simplex virus-related particle.
J Gen Virol. 1991 Mar;72 ( Pt 3):661-8 PMID: 1848601
Evaluation of glucocorticoid-induced DNA fragmentation in mouse thymocytes by flow cytometry.
Cell Prolif. 1991 Sep;24(5):447-59 PMID: 1657218
Membrane-expressed HIV envelope glycoprotein heterodimer is a powerful inducer of cell death in uninfected CD4+ target cells.
Res Virol. 1995 Jan-Feb;146(1):5-17 PMID: 7754236
Apoptosis in viral infections.
Adv Virus Res. 1995;45:1-60 PMID: 7793322
Photochemical inactivation of DNA and RNA viruses by psoralen derivatives.
J Gen Virol. 1978 Aug;40(2):345-58 PMID: 211184
Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation.
Nature. 1980 Apr 10;284(5756):555-6 PMID: 6245367
Psoralen inactivation of influenza and herpes simplex viruses and of virus-infected cells.
Infect Immun. 1981 Jun;32(3):1216-26 PMID: 6265375
Electron microscopic studies of bovine viral diarrhea virus in tissues of diseased calves and in cell cultures.
Arch Virol. 1982;71(1):57-74 PMID: 6279056
The cytopathic effect of HIV is associated with apoptosis.
Virology. 1991 Dec;185(2):829-39 PMID: 1683728
The family Herpesviridae: an update. The Herpesvirus Study Group of the International Committee on Taxonomy of Viruses.
Arch Virol. 1992;123(3-4):425-49 PMID: 1562239
A comparison of serological relationships among five ruminant alphaherpesviruses by ELISA.
Arch Virol. 1992;124(3-4):333-41 PMID: 1605741
Genetic relationships between bovine herpesvirus 4 and the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri.
Virology. 1992 Oct;190(2):654-65 PMID: 1325698
Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.
J Exp Med. 1992 Oct 1;176(4):1099-106 PMID: 1402655
Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection.
J Virol. 1992 Dec;66(12):7383-8 PMID: 1331529
Religation of the T cell receptor after primary activation of mature T cells inhibits proliferation and induces apoptotic cell death.
J Immunol. 1993 Jun 15;150(12):5704-15 PMID: 8515084
Impairment of T cell receptor-dependent stimulation in CD4+ lymphocytes after contact with membrane-bound HIV-1 envelope glycoprotein.
Virology. 1994 Jan;198(1):360-5 PMID: 7903129
Apoptosis: a mechanism of cell killing by influenza A and B viruses.
J Virol. 1994 Jun;68(6):3667-73 PMID: 8189504
Simultaneous determination of cell surface antigens and apoptosis.
Trends Genet. 1994 Feb;10(2):41-2 PMID: 8191583
Activation-induced apoptosis in lymphocytes.
Curr Opin Immunol. 1994 Jun;6(3):476-87 PMID: 7917117
Nonspecific suppressive effect of bovine herpesvirus type 1 on bovine leukocyte functions.
Infect Immun. 1983 Oct;42(1):106-12 PMID: 6311742

Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.70.6.4116-4120.1996

hanon@stat.fmv.ulg.ac.be

Published

1996-06-00

Pages

4116-20

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC190298

Subset

External Links

PubMed source DOI: 10.1128/JVI.70.6.4116-4120.1996 PMC Full Text View journal details

Analysis Services

Inactivated bovine herpesvirus 1 induces apoptotic cell death of mitogen-stimulated bovine peripheral blood mononuclear cells.

Contact

WeChat Official Account