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PMID: 8647369 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Response of Mycobacterium smegmatis to acid stress.

FEMS microbiology letters ·Vol. 139 ·No. 1 ·1996-05-15 ·Pages 11-7

O'Brien LM, Gordon SV, Roberts IS, Andrew PW

Abstract

Evidence was sought for the existence of an inducible acid tolerance response in Mycobacterium smegmatis. Exposure of M. smegmatis to a sub-lethal, adaptive acidic pH was found to confer a significant level of protection against subsequent exposure to a lethal pH, compared to unadapted cells. Adaptation was dependent on de novo protein synthesis.

MeSH Terms

Acids/pharmacology Adaptation, Physiological/drug effects Chloramphenicol/pharmacology Hydrogen-Ion Concentration Mycobacterium/drug effects,growth & development Time Factors

Chemicals

Acids Chloramphenicol

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

O'Brien L M

Department of Microbiology and Immunology, University of Leicester, UK.

Gordon S V

Roberts I S

Andrew P W

Article Info

Journal

FEMS microbiology letters

Abbr.

FEMS Microbiol Lett

ISSN

0378-1097

DOI

10.1111/j.1574-6968.1996.tb08173.x

Published

1996-05-15

Pages

11-7

Language

English

Region

England

NLM ID

7705721

Subset

Grants

Wellcome Trust · United Kingdom

External Links

PubMed source DOI: 10.1111/j.1574-6968.1996.tb08173.x View journal details

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Response of Mycobacterium smegmatis to acid stress.

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