Use of normal daughters' and sisters' creatine kinase levels in estimating heterozygosity in Duchenne muscular dystrophy.

Human heredity ·Vol. 27 ·No. 2 ·1977-00-00 ·Pages 118-26

Emery AE, Holloway S

Abstract

A modification is given of the original density function formula of EMERY and MORTON for estimating heterozygosity in X-linked Duchenne muscular dystrophy. This modification takes into account SCK levels in both normal sisters and normal daughters of a suspected carrier in families where there is only one affected male.

MeSH Terms

Creatine Kinase/blood Female Genes, Recessive Genetic Linkage Heterozygote Humans Male Muscular Dystrophies/genetics Pedigree Sex Ratio Statistics as Topic

Chemicals

Creatine Kinase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Emery A E

Holloway S

Article Info

Journal

Human heredity

Abbr.

Hum Hered

ISSN

0001-5652

DOI

10.1159/000152860

Published

1977-00-00

Pages

118-26

Language

English

Region

Switzerland

NLM ID

0200525

Subset

External Links

PubMed source DOI: 10.1159/000152860 View journal details

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Use of normal daughters' and sisters' creatine kinase levels in estimating heterozygosity in Duchenne muscular dystrophy.

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