Mutations in the X-linked and autosomal recessive forms of chronic granulomatous disease.

Base Sequence Cell Membrane/enzymology Chromosomes, Human, Pair 1/genetics Chromosomes, Human, Pair 16/genetics Chromosomes, Human, Pair 7/genetics Consensus Sequence Cytochrome b Group/chemistry,deficiency,genetics Cytoplasmic Granules/enzymology Female Genes, Recessive Genetic Heterogeneity Genetic Therapy Granulomatous Disease, Chronic/classification,enzymology,genetics,therapy Humans Interferon-gamma/therapeutic use Leukocytes/enzymology,ultrastructure Male Membrane Glycoproteins/genetics Membrane Transport Proteins Models, Molecular Molecular Sequence Data Mutation NADH, NADPH Oxidoreductases/chemistry,deficiency,genetics NADPH Dehydrogenase/genetics NADPH Oxidase 2 NADPH Oxidases Phosphoproteins/genetics Protein Conformation Recombinant Proteins Sequence Deletion X Chromosome/genetics

Cytochrome b Group Membrane Glycoproteins Membrane Transport Proteins Phosphoproteins Recombinant Proteins neutrophil cytosol factor 67K Interferon-gamma cytochrome b558 NADH, NADPH Oxidoreductases CYBB protein, human NADPH Oxidase 2 NADPH Oxidases CYBA protein, human neutrophil cytosolic factor 1 NADPH Dehydrogenase