Protein sorting by transport vesicles.

Science (New York, N.Y.) ·Vol. 272 ·No. 5259 ·1996-04-12 ·Pages 227-34

Rothman JE, Wieland FT

Abstract

Eukaryotic life depends on the spatial and temporal organization of cellular membrane systems. Recent advances in understanding the machinery of vesicle transport have established general principles that underlie a broad variety of physiological processes, including cell surface growth, the biogenesis of distinct intracellular organelles, endocytosis, and the controlled release of hormones and neurotransmitters.

MeSH Terms

Amino Acid Sequence Animals Biological Transport Cell Compartmentation Cell Membrane/metabolism Coated Vesicles/metabolism Endocytosis Endoplasmic Reticulum/metabolism Golgi Apparatus/metabolism Hormones/metabolism Intracellular Membranes/metabolism Membrane Fusion Membrane Proteins/metabolism Molecular Sequence Data Neurotransmitter Agents/metabolism Organelles/metabolism Proteins/metabolism

Chemicals

Hormones Membrane Proteins Neurotransmitter Agents Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Rothman J E

Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, 10021, USA.

Wieland F T

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.272.5259.227

Published

1996-04-12

Pages

227-34

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.272.5259.227 View journal details

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