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PMID: 8602158 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The biallelic a mating type locus of Ustilago maydis: remnants of an additional pheromone gene indicate evolution from a multiallelic ancestor.

Molecular & general genetics : MGG ·Vol. 250 ·No. 4 ·1996-03-07 ·Pages 414-20

Urban M, Kahmann R, Bölker M

Abstract

The a mating type locus of Ustilago maydis contains the structural genes for a pheromone-based cell recognition system that governs fusion of haploid cells. The locus exists in two alleles, termed a1 and a2. We have completed the analysis of the nucleotide sequences unique to a1 and a2. Within these dissimilar regions we find two short patches of DNA sequence similarity. Interestingly, one of these segments corresponds to the transcribed region of the a1 pheromone precursor. As a result of multiple nucleotide exchanges this sequence does not code for a functional product. The existence of a second pheromone gene in the a2 allele suggests that the present locus had a multiallelic ancestor. In addition, we describe the presence of two additional genes in the a2 allele. We have investigated the role of these genes during mating and pathogenic development and speculate that they might affect mitochondrial inheritance.

MeSH Terms

Alleles Amino Acid Sequence Base Sequence DNA, Complementary/genetics DNA, Fungal/genetics Evolution, Molecular Genes, Fungal/genetics Genes, Mating Type, Fungal Molecular Sequence Data Mutagenesis, Insertional Pheromones/genetics Reproduction Sequence Analysis, DNA Ustilago/genetics,physiology

Chemicals

DNA, Complementary DNA, Fungal Pheromones

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Urban M

Institut für Genetik und Mikrobiologie der Universität München, München, Germany.

Kahmann R

Bölker M

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24 references, click to expand

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Article Info

Journal

Molecular & general genetics : MGG

Abbr.

Mol Gen Genet

ISSN

0026-8925

DOI

10.1007/BF02174029

Published

1996-03-07

Pages

414-20

Language

English

Region

Germany

NLM ID

0125036

Subset

Databases

GENBANK

U37795, U37796

External Links

PubMed source DOI: 10.1007/BF02174029

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The biallelic a mating type locus of Ustilago maydis: remnants of an additional pheromone gene indicate evolution from a multiallelic ancestor.

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