Are bacterial proteinases pathogenic factors?

Trends in microbiology ·Vol. 3 ·No. 10 ·1995-10-00 ·Pages 405-7

Travis J, Potempa J, Maeda H

Abstract

Evidence is rapidly accumulating that suggests that the growth and proliferation of pathogenic bacteria depend on proteolytic enzymes of the invading organism and of the host. Proteinase inhibitors targeting bacterial proteinases may be useful antimicrobial agents.

MeSH Terms

Animals Bacteria/enzymology,pathogenicity Bacterial Infections/drug therapy,microbiology Bacterial Proteins/drug effects,physiology Endopeptidases/drug effects,physiology Humans Kallikreins/metabolism Kinins/metabolism Protease Inhibitors/therapeutic use Virulence

Chemicals

Bacterial Proteins Kinins Protease Inhibitors Endopeptidases Kallikreins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Travis J

Dept of Biochemistry, University of Georgia, Athens 30602, USA.

Potempa J

Maeda H

Article Info

Journal

Trends in microbiology

Abbr.

Trends Microbiol

ISSN

0966-842X

DOI

10.1016/s0966-842x(00)88988-x

Published

1995-10-00

Pages

405-7

Language

English

Region

England

NLM ID

9310916

Subset

External Links

PubMed source DOI: 10.1016/s0966-842x(00)88988-x View journal details

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