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PMID: 8559668 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A cre-transgenic mouse strain for the ubiquitous deletion of loxP-flanked gene segments including deletion in germ cells.

Nucleic acids research ·Vol. 23 ·No. 24 ·1995-12-25 ·Pages 5080-1

Schwenk F, Baron U, Rajewsky K

Abstract

暂无摘要

MeSH Terms
Animals DNA Nucleotidyltransferases/genetics Gene Deletion Germ Cells Integrases Mice Mice, Transgenic Recombination, Genetic Viral Proteins
Chemicals
Viral Proteins Cre recombinase DNA Nucleotidyltransferases Integrases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Schwenk F
Institute for Genetics, University of Cologne, Germany.
Baron U
Rajewsky K
References (11)
11 references, click to expand
  1. Bacteriophage P1 site-specific recombination. I. Recombination between loxP sites.
    J Mol Biol. 1981 Aug 25;150(4):467-86 PMID: 6276557
  2. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.
    Proc Natl Acad Sci U S A. 1988 Jul;85(14):5166-70 PMID: 2839833
  3. Dissection of thymocyte signaling pathways by in vivo expression of pertussis toxin ADP-ribosyltransferase.
    EMBO J. 1990 Dec;9(12):3821-9 PMID: 2123451
  4. Targeted oncogene activation by site-specific recombination in transgenic mice.
    Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6232-6 PMID: 1631115
  5. Tissue- and site-specific DNA recombination in transgenic mice.
    Proc Natl Acad Sci U S A. 1992 Aug 1;89(15):6861-5 PMID: 1495975
  6. Co-regulation of two gene activities by tetracycline via a bidirectional promoter.
    Nucleic Acids Res. 1995 Sep 11;23(17):3605-6 PMID: 7567477
  7. Generation of a mouse strain that produces immunoglobulin kappa chains with human constant regions.
    Science. 1993 Nov 19;262(5137):1271-4 PMID: 8235658
  8. Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting.
    Science. 1994 Jul 1;265(5168):103-6 PMID: 8016642
  9. X-chromosome inactivation: molecular mechanisms and genetic consequences.
    Trends Genet. 1994 Jul;10(7):230-5 PMID: 8091502
  10. Inducible gene targeting in mice.
    Science. 1995 Sep 8;269(5229):1427-9 PMID: 7660125
  11. Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting.
    Cell. 1993 Jun 18;73(6):1155-64 PMID: 8513499
Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
Published
1995-12-25
Pages
5080-1
Language
English
Region
England
NLM ID
0411011
PMCID
PMC307516
Subset
IM
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