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PMID: 854739 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

H-y antigen: expression in human subjects with the testicular feminization syndrome.

Science (New York, N.Y.) ·Vol. 196 ·No. 4290 ·1977-05-06 ·Pages 655-6

Koo GC, Wachtel SS, Saenger P, New MI, Dosik H, Amarose AP, Dorus E, Ventruto V

Abstract

Androgen-insensitive subjects with a 46,XY karotype develop as phenotypic females despite presence of testes. The white blood cells of these females type H-Y antigen-positive indicate that expression of the H-Y cell surface component is androgen-independent.

MeSH Terms

Androgen-Insensitivity Syndrome/genetics,immunology Histocompatibility Antigens/analysis Humans Male Sex Chromosomes/immunology Testis/embryology Testosterone/physiology

Chemicals

Histocompatibility Antigens Testosterone

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Koo G C

Wachtel S S

Saenger P

New M I

Dosik H

Amarose A P

Dorus E

Ventruto V

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.854739

Published

1977-05-06

Pages

655-6

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.854739 View journal details

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