Cell cycle. The only way out of mitosis.

Current biology : CB ·Vol. 5 ·No. 9 ·1995-09-01 ·Pages 970-2

Glotzer M

Abstract

The ubiquitination and destruction of cyclins provides the way out of mitosis. A multiprotein complex polyubiquitinates cyclin B and promotes the separation of sister chromatids.

MeSH Terms

Anaphase/physiology Anaphase-Promoting Complex-Cyclosome Animals Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome Apc6 Subunit, Anaphase-Promoting Complex-Cyclosome Cell Cycle Cell Cycle Proteins/metabolism Cyclins/metabolism Humans Mitosis Saccharomyces cerevisiae Proteins Ubiquitin-Protein Ligase Complexes Ubiquitin-Protein Ligases Ubiquitins/metabolism

Chemicals

Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome Apc6 Subunit, Anaphase-Promoting Complex-Cyclosome CDC16 protein, human CDC27 protein, S cerevisiae CDC27 protein, human Cell Cycle Proteins Cyclins Saccharomyces cerevisiae Proteins Ubiquitins Ubiquitin-Protein Ligase Complexes Anaphase-Promoting Complex-Cyclosome Ubiquitin-Protein Ligases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Glotzer M

Cell Biology Program, EMBL, Heidelberg, Germany.

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/s0960-9822(95)00190-4

Published

1995-09-01

Pages

970-2

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/s0960-9822(95)00190-4 View journal details

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