The spectrum of mutations at the p53 locus. Evidence for tissue-specific mutagenesis, selection of mutant alleles, and a "gain of function" phenotype.

Alleles Amino Acid Sequence Animals Chromosome Mapping Chromosomes, Human, Pair 17 Codon/genetics Female Frameshift Mutation Genes, p53 Humans Male Mice Molecular Sequence Data Mutagenesis Mutation Neoplasms/genetics Organ Specificity Phenotype Point Mutation Sequence Homology, Amino Acid Tumor Suppressor Protein p53/biosynthesis,chemistry,genetics Xenopus

Codon Tumor Suppressor Protein p53